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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
8.48
Human Site:
S322
Identified Species:
14.36
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S322
S
N
F
P
E
P
P
S
F
S
P
V
V
D
S
Chimpanzee
Pan troglodytes
XP_509441
819
90122
L282
T
V
S
L
P
D
S
L
I
A
P
P
T
A
P
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Dog
Lupus familis
XP_546925
857
93734
S322
S
H
F
P
E
P
P
S
F
G
P
M
A
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S322
S
N
Y
I
E
S
P
S
F
G
P
M
A
D
S
Rat
Rattus norvegicus
Q6AXT8
471
49872
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
C322
L
G
Y
Q
E
P
P
C
F
E
P
L
Y
G
S
Frog
Xenopus laevis
NP_001084764
548
60887
K61
P
H
S
E
H
P
P
K
K
G
Y
D
F
D
T
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
P315
P
V
F
P
S
T
S
P
T
A
P
S
V
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
F317
K
S
A
S
T
G
T
F
L
N
V
P
R
Q
T
Honey Bee
Apis mellifera
XP_394429
1014
115124
R440
Q
Q
R
N
T
Y
Q
R
T
A
Q
Q
Q
N
S
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
T325
N
D
R
D
T
M
R
T
P
T
N
D
Q
P
S
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
N438
D
L
N
L
S
N
G
N
L
I
L
N
P
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
H536
P
P
T
P
S
P
P
H
P
V
R
P
Q
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
0
66.6
N.A.
60
0
N.A.
N.A.
40
20
26.6
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
20
0
80
N.A.
73.3
0
N.A.
N.A.
53.3
33.3
33.3
N.A.
20
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
22
0
0
15
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
8
0
0
0
0
0
15
0
29
0
% D
% Glu:
0
0
0
8
29
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
22
0
0
0
0
8
29
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
8
8
0
0
22
0
0
0
8
0
% G
% His:
0
15
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
8
8
0
15
0
0
0
8
15
0
8
8
0
15
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
15
0
0
0
% M
% Asn:
8
15
8
8
0
8
0
8
0
8
8
8
0
8
0
% N
% Pro:
22
8
0
29
8
36
43
8
15
0
43
22
8
8
29
% P
% Gln:
8
8
0
8
0
0
8
0
0
0
8
8
22
8
0
% Q
% Arg:
0
0
15
0
0
0
8
8
0
0
8
0
8
0
0
% R
% Ser:
22
8
15
8
22
8
15
22
0
8
0
8
0
0
36
% S
% Thr:
8
0
8
0
22
8
8
8
15
8
0
0
8
8
15
% T
% Val:
0
15
0
0
0
0
0
0
0
8
8
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
8
0
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _